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Fighting Cardiovascular Diseases with in silico Solutions

Computational modeling and simulation (CM&S) of cardiovascular devices and their working environment — the human body and heart — is the most promising way to accelerate and amplify medical innovation while limiting the risk for the patients through in silico research, in silico testing, and in silico clinical trials. 

Ansys simulations go beyond an advanced cardiovascular system model by using multiscale, multiphysics simulations in a suite of connected tools to provide a complete and pragmatic solution.


Optimize Cardiovascular Devices Through Simulation

With more than 30 percent of all deaths attributed to cardiovascular diseases, the healthcare industry invests massively in disease prevention, treatment and efforts to shorten the recovery period. The extensive in vitro and in vivo testing required to ensure patient safety inevitably slows the delivery of innovative implantable cardiovascular devices — stents, valves or pacemakers/defibrillators — to those who need them the most.  Leveraging the power of in silico medicine and developing a detailed and reliable multiphysics model of the device and its working environment (the human body) provides the necessary insights to test and optimize new products, help accelerate regulatory approval and save lives.

 

Ansys Advantage Magazine 2024 Issue I: Simulation Transforms Healthcare

Upcoming Webinars and Events


Interested in Other Healthcare Applications?

Visit our healthcare industry page to learn about more healthcare applications that can benefit from modeling and simulation. 

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Webinars

Below is a list of past webinars held in conjunction with partners, industry, and hospital presenters regarding the work that is being done in the Cardiovascular space at Ansys

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Digital Twins in Cardiology: Dream or Reality?

Despite significant advances in cardiovascular medicine, major challenges persist—such as predicting sudden cardiac death, interpreting complex fibrotic imaging, tailoring catheter ablation, guiding transcatheter valve interventions, and planning intricate surgical procedures. In this session, Dr. Bessiere and Dr. El Houari explore how digital twins, powered by the PyAnsysHeart platform show how modeling is helping deliver more precise and effective cardiovascular care.

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Exploiting Computational Power Delivers Better Therapies, Faster

This presentation highlights Medtronic GTI’s use of a three-physics heart model to improve therapy design. It explores simulation as a rapid prototyping tool—most effective when combined with other evidence—and how modeling is disrupting medtech, as it once did in automotive and aerospace. We’ll also cover the evolving needs of the biomedical industry and share notable public Medtronic GTI successes in modeling and simulation.

Cardiovascular Symposium Spring 2025

Cardiovascular Symposium - Spring 2025

This two-hour event brings together professionals from industry, academia, and regulatory agencies to share their evolving perspectives on cardiovascular modeling and highlight current collaboration needs. Attendees will review ongoing modeling activities and explore partnership opportunities. The event seeks to build a collaborative ecosystem, enhances communication among stakeholders, and ultimately improves patient outcomes in cardiovascular care through shared expertise.


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Using In Silico Evidence to Accelerate the Regulatory Approval of Cardiovascular Devices

Traditionally, the medical device industry has relied on bench, animal, and clinical testing to demonstrate safety and effectiveness. With the growing use of computational modeling and simulation (CM&S), regulatory frameworks are evolving to support this emerging source of evidence. This webinar will review the standard, relevant FDA guidance, and global progress in regulatory acceptance of CM&S.

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From Isolated Simulations to Holistic Workflows: Design of Transcatheter Valve Replacements

Designing transcatheter valve replacements is challenging because manufacturing, treatment preparation, and deployment affect the implant’s final shape, performance, and fatigue life. While mechanical simulations and fatigue analysis are well established, defining realistic boundary conditions for cyclic motion remains complex, often relying on 4D patient scans from early clinical studies.

Heart Modeling

In-silico Modeling of the Patient-specific Heart

By coupling the structural heart model with the ventricular blood compartment, we can accurately simulate venous return by ensuring volume conservation within the closed-loop circulatory system. This integration results in a monolithic, multifield system of equations that captures the complex interactions between cardiac tissue mechanics and blood flow dynamics. Such a physiologically meaningful solution enables advanced in silico modeling.


Ansys Connect Healthcare Webinar

Using Digital Transformation to Streamline Medical Device Development

Healthcare companies face challenges like evolving regulations and supply chain shocks. This webinar explores how Ansys technologies—simulation, digital thread, and data digitalization—help streamline medical device development. We’ll cover materials data, compliance, and V&V40 use cases to de-risk regulation and speed market launch.

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3D Modeling and Flow Simulation in Complex Congenital Heart Disease

The engineering team at Boston Children’s Hospital performs virtual surgery on 3D models to reflect the planned operation or several options for repair. The use of 3D modeling and computational fluid dynamics has been transformational in the treatment of children with some of the most complex congenital heart diseases.

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Using Predictive Engineering to Power Full-Life Cycle Product Development

Eric Corndorf of Medtronic highlights the vital role predictive engineering plays throughout all phases of a development lifecycle. He emphasizes how each team member uniquely contributes to sponsoring and advancing predictive engineering to drive better outcomes in medical device development.

Success Stories and Thought Leadership

Below is a currated list of success stories and thought leadership from our collegues, customers, and partners around the world using simulation to advance cardiovascular medical devices. 

 

Avaliable E-Books

Blogs

Case Studies

 

 

Interested in Other Healthcare Applications?

Visit our healthcare industry page to learn about more healthcare applications that can benefit from modeling and simulation. 

hero-form-healthcare.jpg